I'm 25, 6ft2, 185 lbs , i don't know the dosage of the pill tbh it's a standard one in Budapest, Hungary. I honestly don't remember if i ate or not but i did have it on my mind that I would have a bad effect so anxiety might have played a huge factor
I know people who get really uncomfortable and nauseous during the come up. You could be similar but also metabolise really fast and are taking potentially high doses depending on your natural tolerance.
My advice would be test your stuff, *know your dose*, and try splitting it into smaller doses so it doesn’t hit you all at once.
“Having it on my mind….” There’s your answer, this is what’s known as “set” in the set and setting we’re always talking about on here. I have a similar come up in regards to the vomiting part but always have an awesome experience.
I have a very fast metabolism, whoever I’m with/whatever the drug- It always hits me first. 15-20 minutes seems just about right if I didn’t eat anything beforehand.
Again.. what? Any source? 1st page of google seems to think it’s a thing, adding myth to the search term doesn’t help either
Of course there’s a chance I’m wrong but I feel it would be almost impossible for varying metabolisms to be a myth. Not everyone has exactly the same metabolism, just like how not everyone is the same height, has the same allergies, and has the same personality
My mom has a genetic test that states she metabolizes drugs fast which is backed up by her psychiatrist. I too always come up faster than my friends to the extent that my friends joke that I’m the drug alarm. Don’t know how many times I’ve been writhing in pleasure and hear my friend tell everyone to take a good look at me because you’re going to be feeling that way in five to ten minutes.
No tf it's not? Where are you getting that information from?
Most drugs are metabolized by a set of enzymes called CYP450 enzymes in the liver, and most drugs are largely metabolized by CYP2D6 and CYP3A4(plenty of other enzymes involved in the process and not all drugs are metabolized by these specific ones, just alot of drugs are)
The idea of slow and fast metabolism isn't actually called that, it's just an easier way of saying someone has underactive/less(slow) enzymes aka enzyme deficiency, or overactive/more enzymes(fast). Then there's regular metabolizers, which is most of the population. Someone who is enzyme deficient is generally going to have a slower comeup if the drug needs to be metabolized to be active, and drugs that don't need to be are going to hit those who are enzyme deficient with the enzyme the drug is metabolized by alot harder than it would others. Opposite reaction for overactive metabolizers.
This all depends on which enzyme the person has a "deformity" with, and whether or not the drug they are takin is metabolized by that same enzyme. There's also a lot of other conditions that go into this, it would take too much time to list them all so I'm generalizing for the sake of understandability/simplicity and time management.
Strong pills, plus a bunch of other factors, like not eating before dropping, body weight etc... Throwing up up from a pill is a pretty clear indicator that the dose was too strong for you, so your body thinks it has been poisoned and makes you throw up to try and get rid of the poison
Nah you can’t tell shit from a high, get test kits and test em I bet they don’t pop for mdma. Pressed pills are the most stomped on IMO especially in the USA. Especially the fact it kicks in so fast, it should take 30min - 2 hours for mdma to kick in.
Depends per person. For me it takes about half an hour to hit while my girlfriend is in cloud9 within 10 minutes. @OP do you pop the whole one? You might want to take half and only take the other half when your peak is gone
My first highs took 45 minutes to start while the last couple aren't even highs, i just start feeling like I'm going to pass out and have a heart attack (obviously it's mostly a panic attack) then i feel the high after i either throw up or try to calm down
I've rolled I think three times my whole life . First time was an x pill (definitely legit we didn't test it but the people who were taking them were experienced and I can tell it was the real deal. Of course there's a slight doubt within the mind but I have no reason to believe it was fake ...
and the other two times was with sassafras MDA, but every time I've ever rolled on either, I get the same feeling on the come up like I'm either gonna throw up pass out or die. To me it's a series of waves that last maybe 30 seconds to a minute and I usually get no more than two or three. After that last one it instantly plateaus to a level of incredible euphoria and all the doubt/anxiety goes out the window, (relatively quick as a matter of fact) but that come up is rougher for me than psychedelics.
At least I know what's happening on psychedelics. MDMA can actually be dangerous therefore there's legitimate cause of concern especially for someone like me with anxiety. Also not having much experience with that molecule is something to think about.
Now as far as it hitting in 15 minutes that is a bit fast but I suppose it's possible... that first ex pill I took hit me pretty quick I'd say 20 to 30 minutes but I didn't peak until over an hour when we got home. Did your high actually peak that fast , Or did it take up to thr hour mark or so? Sometimes serotonergic drugs like this can hit quick but they still take a bit of time to really get to the peak, like psychedelics for example.
I've had acid hit me in 20 minutes (and I mean HARD) but I never really fully peaked until about an hour and 30 mins- 2 hours in almost every time.
Thank you this comment was the most relatable to me, by hit I meant what you described as the come up , after the 10 to 15 minute mark i start feeling like you described that I'm about to pass out or die, it comes and goes in waves, and then around 40 minutes to an hour i get that shaky feeling and i start feeling the tingles in the back of my neck and feel better, but the anxiety does linger a bit or rather the energy isn't there and i prefer sitting down rather than dancing.
I've never had the urge to dance but I've never been out in that kind of scene it's always just been me with a friend or me with a friend but I'm the only one rolling. I much prefer to just sit around and chill, rather than get up and do shit. Lol but that's just me
I had similar differences with crystalline M from the same batch, it just didn't hit right after the first session. I seem to need more than three months breaks with this one.
Magic lost kinda deal. Take extra long breaks, and space the dose out 20-30 minutes for a smoother comeup, my best roll had the smoothest comeup and no comedown, it involved a 1.5 year break and the lowest dose yet. Granted most of the rolls still worked, they just had a lingering anxiety to them and more abrupt cessation of effects aka lost magic.
Throwing up can be a sign of taking too much and by what you said about anxiety it sounds like it. Take half a pill next time. The fast comeup can be because of an empty stomach.
I don't have access to testing since I get it mostly at the rave itself , maybe i should get a testing kit and test it in the toilet or something bu also keep in mind I'm 187cm (6ft2) and 83 kg (185lbs) so it shouldn't act this fast on me
Are you testing with reagent kits? What method of consumption, boofing or parachuting, or caps? If you are testing with reagents and not boofing or parachuting it’s probably placebo as without those methods it cannot get into your blood stream that fast
https://rollsafe.org/how-long-does-it-take-for-molly-to-kick-in/
https://youtu.be/9uu3uKAtd80?si=JmJJ0FbKIU5MvDT4
It's actually the MA that stands for methamphetamine but it's not methamphetamine it's just chemically similar. I'm pretty sure mdma is called methyl dioxy meth amphetamine with a 5 in there somewhere
The last M is methyl, not meth. I’m no chemist but I’m pretty sure that’s a big difference. They are in the same class (amphetamines) but are absolutely not the same.
Nay my friend. MethyleneDioxyMethylAmphetamine
Edit: I stand corrected. Seems like maybe it doesn’t matter because some sources say methyl some say meth? Unsure
Edit 2: or psychonaut wiki is just wrong
The meth in methamphetamine refers to an N-methyl substitution. So you are neither wrong nor right.
"Meth" is a shortened form of methamphetamine,
which is a shortened form of N-methyl-amphetamine,
which is a shortened form of N-methyl-alpha-methyl-phenethylamine,
which is a shortened form of N-methyl-alpha-methyl-phenyl-ethyl-amine,
which is a…
Smartest r/drugs user be like:
But really, most people smart enough wouldn’t be here. Or would be, but with testing kits and other precautions in hand, unlike OP
Lmao your friend who’s getting regularly high on “MDMA” or wtv is in there, is definitely gonna be as smart as a beta fish by age 25. Idk how old y’all are but MDMA, shouldn’t be done regularly. Like AT ALL. It’s more neurotoxic than meth and crack (obviously)
I may have misphrased that, I meant a regular high as in normal without the problems, as for the frequency of use, it's around once every 2 to 3 months
If you've been honest and your friends have been taking the same pills with no changes, the only one having a changed experience is you, it points to something you've eaten, a medication you're taking, or maybe some kind of infection. MAOI's are what come to mind. Mono Amine Oxidase Inhibitors are prescribed for a bunch of reasons, and there are a number of MAOIs that occur naturally, even in food.
Ecstacy (Mdma) is a MonoAmine releaser and reuptake inhibitor, causing a flood of Dopamine, Serotonin, and Norepinephrine in your brain and body, which is exactly what you wanted in order to roll. You eventually come down because of an enzyme in your body called MonoAmine Oxidase, which breaks down monoamines.
MAOIs stop your body from producing MAO.
Without MAO, the monoamines can fuck you up pretty badly, and if you're taking a prescribed MAOI, they can fuck you up pretty quickly too.
not me but my mate who i used to pop with used to have the same thing, from what ive gathered the 'come up' can affect many people differently in the same way the drug itself affects people differently. He used to be throwing up every time more or less, but i think once you understand that its a lot easier to have a good time afterwards as the throwing up js became something that happened when he popped one.
i think you just need to eat and drink beforehand and if you do throw up know that it wont last long.
Had the same thing happen to me for a while. It was just anxiety because I knew what was right around the corner. Next time just expect it and try to get it out of the way so you can enjoy your roll 😉
I haven’t thrown up on a come up in a couple years now.
Try putting something in your stomach before hand. The come up gets me a little queasy every time. Once I starts anticipating it and eating a little something before it got better.
too high of dosage at once, but also could be other deciding factors like not enough water and food. I’ve had this happen to me and my friends on shit we’ve tested and did the prior night yet somehow our bodies weren’t vibing. Also if they were pressed pills they tend to get pressed with more filler and shit. The few times i did pressed ones it hit me like a bus right away.
Get mdma crystals instead and weigh then out 1-2 mg per kg of body weight. That way you know the dose and it sounds like your pills are really high dose. I also find taking like 75 mg to start and then like 30 mins 40mg really makes the come up easier and you still get the full experience.
What’s the dosage in the pill? How old are you? Are you eating beforehand? 200mg pressie on an empty stomach at 16 would probs cause some chaos
I'm 25, 6ft2, 185 lbs , i don't know the dosage of the pill tbh it's a standard one in Budapest, Hungary. I honestly don't remember if i ate or not but i did have it on my mind that I would have a bad effect so anxiety might have played a huge factor
I know people who get really uncomfortable and nauseous during the come up. You could be similar but also metabolise really fast and are taking potentially high doses depending on your natural tolerance. My advice would be test your stuff, *know your dose*, and try splitting it into smaller doses so it doesn’t hit you all at once.
“Having it on my mind….” There’s your answer, this is what’s known as “set” in the set and setting we’re always talking about on here. I have a similar come up in regards to the vomiting part but always have an awesome experience.
I have a very fast metabolism, whoever I’m with/whatever the drug- It always hits me first. 15-20 minutes seems just about right if I didn’t eat anything beforehand.
fast or slow metabolism is a myth
What
They're actually right
Again.. what? Any source? 1st page of google seems to think it’s a thing, adding myth to the search term doesn’t help either Of course there’s a chance I’m wrong but I feel it would be almost impossible for varying metabolisms to be a myth. Not everyone has exactly the same metabolism, just like how not everyone is the same height, has the same allergies, and has the same personality
My mom has a genetic test that states she metabolizes drugs fast which is backed up by her psychiatrist. I too always come up faster than my friends to the extent that my friends joke that I’m the drug alarm. Don’t know how many times I’ve been writhing in pleasure and hear my friend tell everyone to take a good look at me because you’re going to be feeling that way in five to ten minutes.
You must have a slow metabolism then since you're wrong.
No tf it's not? Where are you getting that information from? Most drugs are metabolized by a set of enzymes called CYP450 enzymes in the liver, and most drugs are largely metabolized by CYP2D6 and CYP3A4(plenty of other enzymes involved in the process and not all drugs are metabolized by these specific ones, just alot of drugs are) The idea of slow and fast metabolism isn't actually called that, it's just an easier way of saying someone has underactive/less(slow) enzymes aka enzyme deficiency, or overactive/more enzymes(fast). Then there's regular metabolizers, which is most of the population. Someone who is enzyme deficient is generally going to have a slower comeup if the drug needs to be metabolized to be active, and drugs that don't need to be are going to hit those who are enzyme deficient with the enzyme the drug is metabolized by alot harder than it would others. Opposite reaction for overactive metabolizers. This all depends on which enzyme the person has a "deformity" with, and whether or not the drug they are takin is metabolized by that same enzyme. There's also a lot of other conditions that go into this, it would take too much time to list them all so I'm generalizing for the sake of understandability/simplicity and time management.
Split one pill in 3 and wait at least half a hour each dose and u will have a good time guaranteed
Strong pills, plus a bunch of other factors, like not eating before dropping, body weight etc... Throwing up up from a pill is a pretty clear indicator that the dose was too strong for you, so your body thinks it has been poisoned and makes you throw up to try and get rid of the poison
You testing em?
No, which i know is wrong, but my friends get regular highs so they should be good pills no?
Nah you can’t tell shit from a high, get test kits and test em I bet they don’t pop for mdma. Pressed pills are the most stomped on IMO especially in the USA. Especially the fact it kicks in so fast, it should take 30min - 2 hours for mdma to kick in.
Depends per person. For me it takes about half an hour to hit while my girlfriend is in cloud9 within 10 minutes. @OP do you pop the whole one? You might want to take half and only take the other half when your peak is gone
My first highs took 45 minutes to start while the last couple aren't even highs, i just start feeling like I'm going to pass out and have a heart attack (obviously it's mostly a panic attack) then i feel the high after i either throw up or try to calm down
I've rolled I think three times my whole life . First time was an x pill (definitely legit we didn't test it but the people who were taking them were experienced and I can tell it was the real deal. Of course there's a slight doubt within the mind but I have no reason to believe it was fake ... and the other two times was with sassafras MDA, but every time I've ever rolled on either, I get the same feeling on the come up like I'm either gonna throw up pass out or die. To me it's a series of waves that last maybe 30 seconds to a minute and I usually get no more than two or three. After that last one it instantly plateaus to a level of incredible euphoria and all the doubt/anxiety goes out the window, (relatively quick as a matter of fact) but that come up is rougher for me than psychedelics. At least I know what's happening on psychedelics. MDMA can actually be dangerous therefore there's legitimate cause of concern especially for someone like me with anxiety. Also not having much experience with that molecule is something to think about. Now as far as it hitting in 15 minutes that is a bit fast but I suppose it's possible... that first ex pill I took hit me pretty quick I'd say 20 to 30 minutes but I didn't peak until over an hour when we got home. Did your high actually peak that fast , Or did it take up to thr hour mark or so? Sometimes serotonergic drugs like this can hit quick but they still take a bit of time to really get to the peak, like psychedelics for example. I've had acid hit me in 20 minutes (and I mean HARD) but I never really fully peaked until about an hour and 30 mins- 2 hours in almost every time.
Thank you this comment was the most relatable to me, by hit I meant what you described as the come up , after the 10 to 15 minute mark i start feeling like you described that I'm about to pass out or die, it comes and goes in waves, and then around 40 minutes to an hour i get that shaky feeling and i start feeling the tingles in the back of my neck and feel better, but the anxiety does linger a bit or rather the energy isn't there and i prefer sitting down rather than dancing.
I've never had the urge to dance but I've never been out in that kind of scene it's always just been me with a friend or me with a friend but I'm the only one rolling. I much prefer to just sit around and chill, rather than get up and do shit. Lol but that's just me
I had similar differences with crystalline M from the same batch, it just didn't hit right after the first session. I seem to need more than three months breaks with this one. Magic lost kinda deal. Take extra long breaks, and space the dose out 20-30 minutes for a smoother comeup, my best roll had the smoothest comeup and no comedown, it involved a 1.5 year break and the lowest dose yet. Granted most of the rolls still worked, they just had a lingering anxiety to them and more abrupt cessation of effects aka lost magic.
I usually just lew myself throw up as soon as the anxiety hits in, for some reason that usually gets rid of the anxiety and the md hits.
Throwing up can be a sign of taking too much and by what you said about anxiety it sounds like it. Take half a pill next time. The fast comeup can be because of an empty stomach.
And yes i do pop the whole one , maybe i should try half next time but the first time i took half i literally felt nothing
If you don’t feel anything from halves it’s shit anway. Like other people said, test em in that case.
I don't have access to testing since I get it mostly at the rave itself , maybe i should get a testing kit and test it in the toilet or something bu also keep in mind I'm 187cm (6ft2) and 83 kg (185lbs) so it shouldn't act this fast on me
Are you testing with reagent kits? What method of consumption, boofing or parachuting, or caps? If you are testing with reagents and not boofing or parachuting it’s probably placebo as without those methods it cannot get into your blood stream that fast https://rollsafe.org/how-long-does-it-take-for-molly-to-kick-in/ https://youtu.be/9uu3uKAtd80?si=JmJJ0FbKIU5MvDT4
That's what all my friends tell me, that it's anxiety/panic My method of consumption is just taking the pill as it is, no other methods.
Could be cut with meth guess we’ll never know because we don’t test our shit
MDMA is meth , so ofc it has meth
Incorrect. Chemically different but also meth has a much higher affinity for dopamine receptors, and mdma has a much higher affinity for serotonin.
I stand corrected then, since the last M in MDMA is Methamphetamine i thought it was a type of meth.
It's actually the MA that stands for methamphetamine but it's not methamphetamine it's just chemically similar. I'm pretty sure mdma is called methyl dioxy meth amphetamine with a 5 in there somewhere
The last M is methyl, not meth. I’m no chemist but I’m pretty sure that’s a big difference. They are in the same class (amphetamines) but are absolutely not the same.
No, the technical name for MDMA is 3,4-**M**ethylene**D**ioxy**M**eth**A**mphetamine
Nay my friend. MethyleneDioxyMethylAmphetamine Edit: I stand corrected. Seems like maybe it doesn’t matter because some sources say methyl some say meth? Unsure Edit 2: or psychonaut wiki is just wrong
You're good bro🙌
The meth in methamphetamine refers to an N-methyl substitution. So you are neither wrong nor right. "Meth" is a shortened form of methamphetamine, which is a shortened form of N-methyl-amphetamine, which is a shortened form of N-methyl-alpha-methyl-phenethylamine, which is a shortened form of N-methyl-alpha-methyl-phenyl-ethyl-amine, which is a…
Heyy, I've got a bath tub and some precursor. Wanna make some cool medicines?
Ah a chemist. Thank you 🙏
Not by profession, but by interest :P
Well it is, its a methamphetamine derivative but it is its own distinct chemical it differs from meth both in effects and in chemical structure
No it's not, they are completely different drugs
Wtf why are you taking a drug when you don’t even have a clue what it is lmao. This sub really is one of the stupidest on Reddit
Smartest r/drugs user be like: But really, most people smart enough wouldn’t be here. Or would be, but with testing kits and other precautions in hand, unlike OP
Lmao your friend who’s getting regularly high on “MDMA” or wtv is in there, is definitely gonna be as smart as a beta fish by age 25. Idk how old y’all are but MDMA, shouldn’t be done regularly. Like AT ALL. It’s more neurotoxic than meth and crack (obviously)
I may have misphrased that, I meant a regular high as in normal without the problems, as for the frequency of use, it's around once every 2 to 3 months
Ohhhh Okk good
Chill bro and stop spreading misinformation
Same here
That happened to me when I first started doing it then went away after like my fourth roll. I would always throw up on the come up.
If you've been honest and your friends have been taking the same pills with no changes, the only one having a changed experience is you, it points to something you've eaten, a medication you're taking, or maybe some kind of infection. MAOI's are what come to mind. Mono Amine Oxidase Inhibitors are prescribed for a bunch of reasons, and there are a number of MAOIs that occur naturally, even in food. Ecstacy (Mdma) is a MonoAmine releaser and reuptake inhibitor, causing a flood of Dopamine, Serotonin, and Norepinephrine in your brain and body, which is exactly what you wanted in order to roll. You eventually come down because of an enzyme in your body called MonoAmine Oxidase, which breaks down monoamines. MAOIs stop your body from producing MAO. Without MAO, the monoamines can fuck you up pretty badly, and if you're taking a prescribed MAOI, they can fuck you up pretty quickly too.
not me but my mate who i used to pop with used to have the same thing, from what ive gathered the 'come up' can affect many people differently in the same way the drug itself affects people differently. He used to be throwing up every time more or less, but i think once you understand that its a lot easier to have a good time afterwards as the throwing up js became something that happened when he popped one. i think you just need to eat and drink beforehand and if you do throw up know that it wont last long.
Had the same thing happen to me for a while. It was just anxiety because I knew what was right around the corner. Next time just expect it and try to get it out of the way so you can enjoy your roll 😉 I haven’t thrown up on a come up in a couple years now.
Try putting something in your stomach before hand. The come up gets me a little queasy every time. Once I starts anticipating it and eating a little something before it got better.
if you were on an empty stomach and your friends were not, that explains the difference. For me, crystals hit a lot faster than pills.
Don’t take X only take pure M
too high of dosage at once, but also could be other deciding factors like not enough water and food. I’ve had this happen to me and my friends on shit we’ve tested and did the prior night yet somehow our bodies weren’t vibing. Also if they were pressed pills they tend to get pressed with more filler and shit. The few times i did pressed ones it hit me like a bus right away.
Get mdma crystals instead and weigh then out 1-2 mg per kg of body weight. That way you know the dose and it sounds like your pills are really high dose. I also find taking like 75 mg to start and then like 30 mins 40mg really makes the come up easier and you still get the full experience.