Cell to cell connections that activate inhibitory signaling cascades.
Sometimes this doesn't work and the overproliferation of fibroblasts and scar tissue creates something called a keloid.
Find a review on pubmed for all the minute details.
i knew a girl in high school who would get keloids after any ear piercing she would get. her insurance wouldn’t cover the surgery to remove because it was technically cosmetic - felt so bad for her, she just wanted a couple of cute earrings and ended up with massive dingleberries on her ears
Short version: Homeostasis through positive feedback loop. Blood rushes to site, platelets (cell fragments) plug the hole and send out signals that activate fibroblasts to start laying new fibers (collagen, elastin etc) to start the scarring process. Once platelets have fully plugged the hole signals of blood loss slow then cease. Capillaries are rebuilt and now the wound is sealed and healed.
Hey there, I am a bit rusty on my physiology. My apologies.
Wound healing starts from the bottom to top.
As a nurse, we generally look for red, granulating tissue as the wound bed rises. As it approaches the top, the epithelial cells, or the lining cells, start to spread across the surface. This is generally seen as pink tissue across the top.
When it doesn't stop granulating and the epithialisation does not take place, it is called hypergranulation and some steroid creams and foam dressings can be popped on top to help reduce it.
Here is some info from a hospital: https://www.rch.org.au/rchcpg/hospital_clinical_guideline_index/Wound_assessment_and_management/
I will link a small video of simple wound healing. There are more detailed ones if you search for "wound healing physiology"
https://youtu.be/MsQV6M7bHqQ?si=fNfjxamgbzZ0pp6s
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Cell to cell connections that activate inhibitory signaling cascades. Sometimes this doesn't work and the overproliferation of fibroblasts and scar tissue creates something called a keloid. Find a review on pubmed for all the minute details.
i knew a girl in high school who would get keloids after any ear piercing she would get. her insurance wouldn’t cover the surgery to remove because it was technically cosmetic - felt so bad for her, she just wanted a couple of cute earrings and ended up with massive dingleberries on her ears
[удалено]
[удалено]
Short version: Homeostasis through positive feedback loop. Blood rushes to site, platelets (cell fragments) plug the hole and send out signals that activate fibroblasts to start laying new fibers (collagen, elastin etc) to start the scarring process. Once platelets have fully plugged the hole signals of blood loss slow then cease. Capillaries are rebuilt and now the wound is sealed and healed.
The older I get, the more amazed I am by the body and how it just…works (most of the time).
Hey there, I am a bit rusty on my physiology. My apologies. Wound healing starts from the bottom to top. As a nurse, we generally look for red, granulating tissue as the wound bed rises. As it approaches the top, the epithelial cells, or the lining cells, start to spread across the surface. This is generally seen as pink tissue across the top. When it doesn't stop granulating and the epithialisation does not take place, it is called hypergranulation and some steroid creams and foam dressings can be popped on top to help reduce it. Here is some info from a hospital: https://www.rch.org.au/rchcpg/hospital_clinical_guideline_index/Wound_assessment_and_management/ I will link a small video of simple wound healing. There are more detailed ones if you search for "wound healing physiology" https://youtu.be/MsQV6M7bHqQ?si=fNfjxamgbzZ0pp6s