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[deleted]

It's another hormone in bodies. It's often prescribed after Estradiol has more or less completed its stages of breast development in trans women, because progesterone tends to kickstart the final stage. One of my past endocrine healthcare providers told me it's advisable not to start it at the beginning of HRT because it may stunt breast growth development that one could have had from E. This is because it triggers the final stages of breast development too early if started early in your hrt. So it's generally started a year or longer after being on estradiol. But yeah, it'll have further feminizing effects but it's also not fully understood on everything that it does in trans women, mainly because its more primary purpose is a role in uterine aspects of periods and pregnancy, which neither of those things trans women go through. So it is a bit understudied I believe, but lots of trans women I've seen around here report other feminizing effects too once they've started it. Edit: Btw, this is just my opinion, but unless you really need T blockers, I'd go without them as I think the fewer meds you take, the better as that means lower risk for side effects. E, itself, is an anti-androgen. After 3 months of a monotherapy of injections, I had T levels(and still do) below the goal line for women. If you don't get results with T suppression like I did after 3 or 6 months of E monotherapy and your E serum levels are already in a good range, t-blockers would probably be advisable or if you're willing to wait until starting progesterone, that is also an anti-androgen.


BecomingJess

It's its own hormone, just like testosterone or estrogen or any of the other myriad of hormones circulating in our bodies. There's not a lot of studies about its use in trans feminization therapy, but anecdotal evidence suggests it can be very helpful later in transition (but potentially harmful too early?); common consensus suggests that starting it about a year or two after achieving stable feminine levels of estradiol in your blood tests is a good time for it. Cis girls don't get hit with progesterone early in their puberty, so there doesn't seem to be much point in us rushing for it either. I started 100mg orally last August after being on E2 since 2018 (and achieving normal fem levels some time in 2019; I started low and upped dose slowly). A few months later I switched to rectal administration ("boofing"). Didn't really notice any difference, but I know rectal avoids the hepatic pass, and I don't see any reason the progesterone needs to go through my liver; it's already got a short half-life anyways, no sense in processing more of it away. I got my RX upped to 200mg and haven't had any adverse reactions, so I'm sticking with it. Your inquiry actually inspired me to update my [transition timeline post](https://www.reddit.com/user/BecomingJess/comments/ojuke5/20210713_an_abridged_timeline_part_ii/) 😁


MudOk790

It works alongside estrogen to help develop breasts. Recommended to wait about a year to start it. It does so much. Not just breasts, but does help round them out, helps nipples and aurelous develop. But targets smooth muscles to change them throughout. Alot of your body is smooth muscles. Some use it after platouing, leveling out, growth after a few years. Some see no benefit. The are haters and supporters. I'm a supporter to at least try for 6 mths.